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We’ve been told that heart disease is a simple math problem: "Lower your ApoB at all costs." But the latest science suggests we’re looking at the scoreboard instead of the game. Your LDL particles aren't just numbers; they are structural delivery trucks. The real question isn't how many trucks are on the road, but what they are carrying and how stable they are. In Part 2 of our deep dive, we break down the 5 Pillars of Vascular Resilience

In the latest health podcasts, the message is clear: "Lower your ApoB at all costs and replace SFA with seed oils or face the consequences." But what if the number of trucks on the road isn't the problem? What if the problem is the cargo? In Part 1 of this series, we go "under the hood" of human biochemistry to debunk the mainstream narrative. We explore the Five Phases of the Lipid Loop

Populations adapted by developing energy-conserving physiology — efficient fat storage, early insulin resistance (to prioritise glucose for the brain), and lower lean muscle mass. But when this “thrifty” biology meets modern abundance — high-refined-carb diets, low physical activity — the same traits become maladaptive:→ less muscle mass, less subcutaneous storage, more spillover into visceral depots.

Peptides aren’t the future — they’re the present. But the real biohack? Mastering your body’s own signaling before you ever touch a vial. Peptides aren't magic—they're biology hacks. Stack smart, test blood work, and pair with whole foods/sleep.

At this point, it’s worth asking: if polyunsaturated seed oils and plant sterols disrupt red blood cells, fuel oxidation, promote inflammation, and crystallise in plaques — then why are they still recommended as “cardioprotective”?

The demonization of saturated fat wasn't malice but a cascade: panic-fueled hypothesis, flawed cornerstone study, buried null results, and politicized policy. Vegetable oil industries lobbied (visiting scientists to yank papers), while a small cadre controlled grants and journals, stifling dissent.

When you drastically reduce your Calories In, your body does not just sit there and accept the deficit. It enacts a powerful survival response called metabolic adaptation or adaptive thermogenesis. You reduce Calories In, and your body reduces Calories Out.

Every decision you make — what to eat, whether to snack, how much to serve — draws on this limited pool of cognitive energy. Psychologists call this decision fatigue: the more choices you face, the weaker your self-control becomes. This is why dieting is so hard. You’re not only fighting hunger hormones and cravings, you’re draining a limited mental resource dozens of times a day. And when it runs out, biology takes over.

If a calorie is not a calorie — if we can’t reliably know how much of it is absorbed, how much is lost in digestion, and what its metabolic fate will be — then how would anyone know how many calories to cut?

And if a calorie is not a calorie — if we can’t reliably know how much of it is absorbed, how much is lost in digestion, and what its metabolic fate will be — then how would anyone know how many calories to cut? Are people expected to constantly battle with calorie math, obsess over every bite, track every number on an app, and then feel guilty for “going over” — even though the body never sees those calories the way the food label does?